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Ginsenoside Rc

CAS No. 11021-14-0

Ginsenoside Rc ( Ginsenoside RC | NSC-310104 | Panaxoside RC | HY-N0042 | S-3837 | CS3837 | CS 3837 )

产品货号. M10392 CAS No. 11021-14-0

人参皂苷 Rc 是一种类固醇糖苷和三萜皂苷,仅在植物人参(人参)属中发现。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥543 有现货
10MG ¥948 有现货
25MG ¥1588 有现货
50MG ¥2365 有现货
100MG ¥3507 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Ginsenoside Rc
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    人参皂苷 Rc 是一种类固醇糖苷和三萜皂苷,仅在植物人参(人参)属中发现。
  • 产品描述
    Ginsenoside Rc is a steroid glycoside, and triterpene saponins, found exclusively in the plant genus Panax (ginseng); have properties that inhibit or prevent tumors growth.(In Vitro):Ginsenoside Rc, one of major Ginsenosides from Panax ginseng, enhances γ-aminobutyric acid (GABA) receptorA (GABAA)-mediated ion channel currents. Ginsenoside Rc enhances GABA-mediated ion currents in oocytes expressing the GABAA receptor. Ginsenoside Rc significantly inhibits the expression of macrophage-derived cytokines, such as TNF-α and IL-1β. Ginsenoside Rc also markedly suppresses the activation of TANK-binding kinase 1/IκB kinase ε/interferon regulatory factor-3 and p38/ATF-2 signaling in activated RAW264.7 macrophages, human synovial cells, and HEK293 cells. Ginsenoside Rc exerts its anti-inflammatory actions by suppressing TANK-binding kinase 1/IκB kinase ε/interferon regulatory factor-3 and p38/ATF-2 signaling. Ginsenoside Rc suppresses the nuclear translocation of phospho-ATF-2 and phospho-FRA-1, whereas the translocation of p65 at its peak time points (30 and 60 min) is not decreased by Ginsenoside Rc treatment. Ginsenoside Rc regulates the expression of the proinflammatory cytokine TNF-α, which is produced by macrophages, by suppressing AP-1 activation.
  • 体外实验
    ——
  • 体内实验
    ——
  • 同义词
    Ginsenoside RC | NSC-310104 | Panaxoside RC | HY-N0042 | S-3837 | CS3837 | CS 3837
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    11021-14-0
  • 分子量
    1079.27
  • 分子式
    C53H90O22
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 10 mM
  • SMILES
    O[C@@H]([C@@H]([C@@H](CO)O1)O)[C@@H](O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)[C@@H]1O[C@H]3CC[C@]4(C)[C@@]5([H])C[C@@H](O)[C@]6([H])[C@@H]([C@@](C)(O[C@H]7[C@@H]([C@H]([C@@H]([C@@H](CO[C@H]8[C@@H]([C@H]([C@H](CO)O8)O)O)O7)O)O)O)CC/C=C(C)\C)CC[C@](C)6[C@@](C)5CCC4C3(C)C
  • 化学全称
    (2R,3S,4S,5R,6S)-2-((((2R,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)methyl)-6-(((2S)-2-((3S,8R,9R,10R,12R,13R,14R,17S)-3-(((2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-12-hydroxy-4,4,8,10,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-6-methylhept-5-en-2-yl)oxy)tetrahydro-2H-pyran-3,4,5-triol

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Yang JW, Kim SS. Molecules. 2015 Jan 14;20(1):1293-303.
产品手册
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